Rational approaches to the treatment of hypertension: drug therapy—monotherapy, combination, or fixed-dose combination?

نویسندگان

چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Rational approaches to the treatment of hypertension: drug therapy—monotherapy, combination, or fixed-dose combination?

Blood pressure (BP) control is inadequate worldwide. Many clinical trials suggest that BP is not satisfactorily controlled using monotherapy in most patients. Free drug or fixed-dose combinations are other therapeutic options. The advantages and disadvantages for different treatment approaches are discussed in this review.

متن کامل

Fixed dose drug combination for treatment of tuberculosis.

877 VOLUME 46__OCTOBER 17, 2009 Anti-tuberculosis therapy (ATT) with multiple antimicrobials, administered individually or as fixed dose combinations (FDC) is the key to control of tuberculosis. Arguments in favour of FDC include better patient compliance, simplification of prescriptions, easier management of drug supply, reduced programmatic cost, and less chances of developing drug resistance...

متن کامل

Fixed-dose combination Therapy in Hypertension: Focus on Fixed-dose combination of Amlodipine and Valsartan (exforge®)

Hypertension is the leading cause of disability and cardiovascular mortality world-wide. Approximately one-third of the US adult population and over a billion people world-wide have hypertension. Despite increased awareness of hypertension and availability of many effective antihypertensive agents, only one third of patients achieve their target blood pressure (BP). All expert panels now recomm...

متن کامل

Treating Special Populations with Hypertension: Is a Two-Drug or Fixed-Dose Combination Therapy Appropriate Initial Treatment in Hypertension?

Currently, physicians are utilizing one or more antihypertensive medications, with lifestyle modifications, to get BP controlled to levels below 140/90 mm Hg. Both in clinical practice and in clinical trials a majority of patients may require two or more antihypertensive drugs to be effectively controlled. Thus, the clinician is challenged to determine whether one or more drugs should be starte...

متن کامل

Fixed-dose triple-combination treatments in the management of hypertension.

Hypertension remains uncontrolled in approximately 50% of patients with hypertension, which increases the risk of cardiovascular morbidity and mortality in these individuals. A key factor contributing to poor blood pressure (BP) control is nonadherence to prescribed antihypertensive medications. Improving patient adherence to antihypertensive therapy is the key to improving BP goal attainment. ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Kidney International Supplements

سال: 2013

ISSN: 2157-1716

DOI: 10.1038/kisup.2013.75